The pathogenesis of organic ED is related to dysfunction of the endothelium. Endothelial cells can become injured through a variety of mechanisms, most of which cause oxidative stress on the tissues. Many of these causes of oxidative stress are related to lifestyle issues which lead to hypertension, diabetes and dyslipidaemia (figure 1). Endothelial cell dysfunction results in reduction of endothelium-dependent vasorelaxation as well as increased adhesion of leukocytes to the endothelium. Endothelial cell injury then leads to a variety of sequelae, including ED, other types of vasoconstriction, atherosclerosis and thrombus formation.18
Pregnancy & BreastfeedingCan I take Viagra (Sildenafil (Injection)) if I’m pregnant or breastfeeding?
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Sometimes, blood flow problems develop because of damage to the endothelium or penile smooth muscle – tissues in the penis that are important for normal erections. This damage may be the result of high blood pressure or smoking. It can also happen if a man has high cholesterol, triglyceride, or blood sugar levels.
30-50% of hypertensive men also suffer from ED. Hypertension can disrupt erectile tissue function. In addition, some prescriptions for the condition can cause ED. However, there’s evidence that suggests that once adequate blood pressure control is regained – even for those on medication – ED becomes less likely.
Sexual Medicine Society of North America: SexHealthMatters: "Treating Erectile Dysfunction" and "Vacuum Devices: Erectile Dysfunction."
Rose essential oil works to fight stress and anxiety, two causes of erectile dysfunction. It’s also known to help balance sex hormones and improve libido. A 2015 double-blind, randomized and placebo-controlled clinical trial that was published in Neuropsychiatric Disease and Treatment found that rose essential oil was able to improve sexual function in males with SSRI-induced sexual dysfunction and major depressive disorder. Using rose oil improved the participant’s self-rated symptoms of depression and helped to improve sexual dysfunction that was caused by medication use. (30)
Erectile dysfunction (ED) is when a man cannot get or keep an erection. The condition prevents the man from having sex or finishing sex. This condition used to be called impotence. ED can occur at any age, but it is more common in men older than 75 years of age.
Injection: The medication is put into the side of the penis by a needle. This raises your risk for dangerously prolonged erections and scarring.
The stress of erectile dysfunction and its toll on self-confidence and/or a relationship can be hard to deal with. Speaking to a psychologist or counselor about how to cope emotionally can be of great benefit to some people.
Harvard T. H. Chan School for Public Health, The Nutrition Source: “Nuts for the Heart.”
The most compelling new treatments being researched are acoustic wave and low-intensity shockwave therapies (LI-SWT). These treatments both use soundwaves, but the much faster-moving shockwaves appear to be more effective at stimulating blood flow and improving vascular performance in penile tissue.
For ED, one systematic review concluded that red ginseng in particular may be effective in the treatment of ED. However, like most OTC ED remedies, additional research is required to provide conclusive evidence.
Beginning in the 1990’s, researchers discovered that using therapeutic, ultrasound wave technology encourages angiogenesis, or the formation of new blood vessels, when searching for treatments for CAD and heart diseases.
You can buy extract of the bark of the yohimbe tree – long used as an aphrodisiac in western Africa -- as a dietary supplement. Its promoters claim it can help erectile dysfunction. But the science shows mixed results.
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Both the 100mg and 200mg dosages take effect in about 15 minutes, which is even faster than BlueChew’s chewable sildenafil. It lasts about six hours, which is basically on par with sildenafil (and Viagra).
6. Pull the needle out of the ampule and lay the syringe on the edge of a flat surface. Make sure the needle hangs over the edge to keep it from touching anything.